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Thursday, July 30, 2020 | History

3 edition of Comparative beta blockade and the ischemic myocardium found in the catalog.

Comparative beta blockade and the ischemic myocardium

Comparative beta blockade and the ischemic myocardium

proceedings of a symposium, Paris, June 27, 1980

  • 163 Want to read
  • 37 Currently reading

Published by Merck Sharp & Dohme in Rahway, N.J .
Written in English

    Subjects:
  • Adrenergic beta blockers -- Congresses.

  • Edition Notes

    StatementDesmond G. Julian, moderator ; [contributions by] E. Neil Moore .. [et al.].
    ContributionsJulian, Desmond G., Moore, E. Neil.
    Classifications
    LC ClassificationsRC684.A35 C66 1981
    The Physical Object
    Paginationvii, 108 p. :
    Number of Pages108
    ID Numbers
    Open LibraryOL15121285M
    ISBN 100935404198
    OCLC/WorldCa10068305

    Kramer JM, Curtis LH, Dupree CS, et al. Comparative effectiveness of beta-blockers in elderly patients with heart failure. Arch Intern Med ; Sin DD, McAlister FA. The effects of beta-blockers on morbidity and mortality in a population-based cohort of 11, elderly patients with heart failure. Am J Med ; Historically, the use of beta-blocker therapy was avoided in patients with systolic HF because the drug effects can diminish myocardial contractility when first introduced. 2,4,6 However, beta-blockers are now known to improve HF signs and symptoms, increase exercise tolerance, and improve left-ventricular systolic function after several months.

    Heart Failure and Myocardial Infarction Case Study Sample Answer. Myocardial Infarction: Case Study. Causes, Incidence, and Risk Factors for Myocardial Infarction. Myocardial infarction (MI) is an impairment of heart functioning characterized by the diminished blood supply to cardiac muscles following myocardial ischemia (Wong et al. that beta-blocker therapy may be associated with reduced long-term mortality after early percutaneous coronary intervention for acute MI(9,10). In stable coronary artery disease (CAD), there is solid evidence to show that beta-blockers effectively relieve anginal symptoms and improve myocardial ischemia (11), and are therefore recommended asCited by: 9.

    We examined the effects of a cardioselective beta-blocking drug on exercise-induced regional myocardial ischemia in 10 conscious dogs with chronic coronary artery stenosis. An Cited by: Noncompliant on antihypertensive therapy was seen in 61%, 71%, and 48 % of the total, myocardial infarction, and stroke groups, respectively. The drug type was 24 % angiotensin converting enzyme inhibitor, % combined drugs, % Beta Blocker, 11 % angiotensin 11 receptor blocker, % calcium channel blocker and % diuretic.


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Comparative beta blockade and the ischemic myocardium Download PDF EPUB FB2

Am J Cardiol. Oct;44(4) Comparative effects of cardioselective versus noncardioselective beta blockade on subendocardial blood flow and contractile function in ischemic by: Comparative Effects of Cardioselective Versus Noncardioselective Beta Blockade on Subendocardial Blood Flow and Contractile Function in Ischémie Myocardium JAMES D.

BUCK GARRETT J. GROSS, PhD DAVID C. WARLTIER, PhD STANLEY R. JOLLY, MS HAROLD F. HARDMAN, PhD, MD Milwaukee, Wisconsin The comparative effects of three beta adrenergic antagonists, bevantolol (Cl Cited by: Limited data are available from a few studies that evaluated the effects of combination anti-ischemic therapy on myocardial ischemia, 27, 30, 32, 33The combination of a β blocker (propranolol, metoprolol, or atenolol) and a calcium antagonist (nifedipine or amlodipine) has been found to have greater anti-ischemic effect than treatment with Cited by: The comparative effects of three beta adrenergic antagonists, bevantolol (CI, a new cardioselective agent), practolol and propranolol, on regional myocardial blood flow Comparative beta blockade and the ischemic myocardium book contractile function distal to a severe flow-limiting stenosis of the left circumflex coronary artery were studied in the anesthetized by: Abstract.

1 The effects of propranolol and practolol, at equivalent myocardial beta-adrenoceptor blocking doses, (as assessed by the degree of shift of isoprenaline dose-response curves) were investigated in anaesthetized greyhounds before and after acute coronary artery ligation.

2 When administered intravenously to the intact close-chest dog, propranolol ( mg/kg) and practolol ( mg/kg Cited by: beta-Blockade and acute myocardial infarction. Lie KI, Fiolet JW.

Results from experimental and clinical studies suggest that beta-blockade may have beneficial effects in acute myocardial infarction. These effects relate to decrease of cardiac work and improvement of metabolism without deleterious effects on perfusion of the ischemic by: 3.

Abstract. To determine whether prior acute Beta blockade protects the heart against the deleterious effects of normothermic low flow global ischemia on myocardial function, aortic pressure, developed pressure, dP/dt max and end diastolic pressure were monitored in isolated perfused rabbit hearts prior to, during and following 30 and 60 min ischemia, during which either Krebs-Henseleit (control Cited by: Myocardial Ischemia Beta Blocker Systolic Time Interval Diastolic Arterial Blood Pressure Relative Ischemia These keywords were added by machine and not by the authors.

This process is experimental and the keywords may be updated as the learning algorithm : R. Muchada. The anti-ischemic effects of β blockers most likely result from decreases in heart rate and contractility, with a decrease in myocardial oxygen demand.

Carvedilol is similar to other β blockers in reducing myocardial oxygen demand by decreasing heart rate and contractility. Background Long-term administration of beta-adrenergic blockers to patients after myocardial infarction improves survival.

However, physicians are reluctant to administer beta-blockers to many pati Cited by: Lambert DMD () Beta blockers and life expectancy in ischemic heart disease. Lancet Multicentre International Study () Improvement in prognosis of myocardial infarction by long-term beta-adrenoceptor blockade using practolol.

Br Med J CrossRef Google ScholarAuthor: F. Waagstein, Å Hjalmarson. The effects of nitrates, calcium-channel blockers, beta-blockers, and statins on myocardial perfusion imaging are likely attributable to changes in myocardial blood flow and myocardial oxygen supply–demand ratio.

This comprehensive review examines Cited by:   Beta-blockers can help reduce mortality following acute myocardial infarction (MI); however, whether beta-blockers exert a class effect remains controversial.

This study identified all Cited by: 5. Beta-blockade consistently improves myocardial systolic function in patients with both nonischemic and ischemic cardiomyopathy.

The effects of beta-blockade on Adriamycin-induced cardiomyopathy (ACM), however, are unknown. We retrospectively evaluated the effects of beta-blockade on patients with ACM by using a case-controlled by: For patients with acute myocardial infarction (MI), beta blocker therapy reduces infarct size and early mortality when started early and lowers the risk of death when continued long term.

(See "Overview of the acute management of ST-elevation myocardial infarction" and "Overview of the acute management of non-ST elevation acute coronary. Principal Findings: Overall, 2, patients were randomized. In the bucindolol group, the mean age was 60 years, 21% were women, 24% were black, 37% were diabetics, 19% were current smokers, mean body mass index was 28 kg/m 2, median duration of heart failure was 36 months, cause of heart failure was ischemic in 59% and idiopathic in 26%, mean blood pressure was /71 mm Hg, and mean left.

Since the mid-late nineties beta-blockade has become one of the pillars of chronic heart failure treatment. Based on a significant and consistent beneficial effect on survival and a reduction of worsening heart failure (HF) in large, placebo-controlled studies performed at that time, beta-blockade has been accepted as mandatory therapy in patients with stable mild, moderate and severe by: ABA Keywords.

ITE Keywords; MOCA Keywords; Expert Voices. Article of the Month; Ask the Expert; Keys to the Cart; SOAP Obstetric Anesthesia Podcast; OB Anesthesia Virtual Obstetric Grand Rounds. American College of Cardiology (ACC) Annual Scientific Sessions Vol Is Supplement, select article BETA BLOCKER POST ACS IN PATIENTS WITH PRESERVED LEFT VENTRICULAR SYSTOLIC FUNCTION select article DIET AND ISCHEMIC BURDEN: A COMPARATIVE ANALYSIS OF A PLANT BASED REGIMEN VERSUS A MEDITERRANEAN.

Evidence from some trials of β-blockers after myocardial infarction suggests that such treatment reduced mortality in selected subgroups of patients with current or previous heart failure.

13 14 At present, the clinical use of β-blockers in patients with heart failure and ischemic heart disease remains limited, reflecting uncertainty about. Perspective: There is variation in guideline recommendations for the use of beta-blockers following AMI in patients without LVSD or HF.

US guidelines recommend beta-blockers for all patients post-AMI regardless of HF or LVSD (Class I), while European guidelines have a Class IIa indication for beta-blocker use in patients without LVSD or HF.

Beta blockers, including carvedilol, also decrease heart rate, myocardial contractility, and myocardial oxygen demand. Carvedilol also decreases .These results imply increased sensitivity to the effects of beta blockade in ischemic myocardium.

In coronary artery disease patients with an abnormal response to exercise and in normal volunteers during beta blockade, propranolol's effect on exercise left ventricular performance was independent of changes in ventricular preload and after load Cited by: